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The CONSERVE 2021 checklist is a reporting guideline developed to improve transparency in trials and observational studies affected by extenuating circumstances such as pandemics, natural disasters, or conflicts. It explains how researchers should report protocol modifications and methodological changes made during unexpected disruptions. The checklist complements existing reporting guidelines like CONSORT and STROBE. CONSERVE 2021 helps authors clearly describe deviations, mitigation strategies, and their impact on study validity. Journals use this checklist to assess credibility and interpretability of disrupted research. It is recommended for studies conducted under exceptional or emergency conditions.
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