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Statistics, Bioinformatics and Modelling

Data and Artificial Intelligence Services

Pubrica provides statistical analysis, bioinformatics, predictive modelling and real-world data analysis for researchers, life-science companies and publishers. Our statisticians and data scientists establish what your data can support, run and validate the analysis, and report it to the standard your destination requires. You receive the code, the log and the working files so your own team can rerun the analysis. Every other Pubrica service group uses this team, which is why it is presented as a separate service group.

  • Feasibility assessed first: many clinical datasets cannot support the model requested, and we tell you this at the start
  • Validation method stated: internal, temporal or external, because the type of validation determines what the result can claim
  • Code, environment and seeds handed over, so the result can be regenerated when a reviewer requests a sensitivity analysis
  • Reported to the standard the destination uses: TRIPOD+AI for prediction models and CONSORT-AI where the intervention is an algorithm
  • Analysis within your own environment, which is usually the right arrangement for identifiable data because only the output leaves your systems
Service groups we support Analysis provided

Research servicesPooling and modelling

Market accessEconomic models and RWE

Medical device & IVDPerformance analysis

Editorial servicesStatistical review

A result decided in advanceNot offered

Data → what it supports → analysis → validation → a defensible claim

Included in every analysis
  • What the data supports, established before modelling
  • Validation strategy fixed in advance
  • Calibration reported, not only discrimination
  • Code, environment and seeds handed over
  • Analysis can run inside your own environment
One service areaUsed by every Pubrica service group
TRIPOD+AIFor clinical prediction models
Code handed overEnvironment, seeds and logs
ISO 9001:2015Quality management certified · cert. H3CR9TCU20251212INDQM10N

Our Services

Data and AI Services Across Pubrica

You can contact this team directly or through any other Pubrica service you already use. The same team carries out the analysis in either case.

Data, analytics & AI · the main service Predictive modelling, algorithm development, segmentation, patient journey analytics, interpretation and visualisation, HEOR analysis and data-led editorial.

Nine servicesA model that performs well only on its development data has not yet been validated.

Biostatistics & programming The analysis itself in R, SAS, Stata, SPSS or Python, with the code, the log and the outputs handed over so your team can rerun it.

Used by almost every other Pubrica teamResults that cannot be regenerated cannot be defended at review.

Bioinformatics Sequencing, expression, variant and pathway analysis with the pipeline, tool versions and parameters recorded so the run is reproducible.

Pipelines, versions, parametersTool versions affect results, and a methods section that omits them cannot be reproduced.

Medical data collection Instrument design, abstraction from records and the quality control that decides whether any of the analysis above is worth running.

Before analysis beginsMany analysis problems originate in how the data was collected.

Interpretation & visualisation Analyses presented as figures and text that readers can act on, with uncertainty shown rather than smoothed away.

Presenting results clearlyOmitting a confidence band from a chart implies a precision the analysis does not support.

Health economics & outcomes research Burden of illness, real-world outcomes and PRO analysis — the evidence that feeds a value story rather than the dossier that carries it.

Feeds market accessThis service provides the analysis. The dossiers and economic models it supports are prepared by our market access team.

Samples are illustrative and anonymised. Hover any one of them to play it again.

Compliance and Standards

Reporting Standards for Data Analysis and AI

Health data analysis is assessed against reporting standards as well as model performance.

+AI

TRIPOD+AI (for clinical prediction models)

The reporting standard for developing and validating prediction models, including the machine-learning extension. It covers the items reviewers ask for.

-AI

CONSORT-AI and SPIRIT-AI (for trials of AI interventions)

Where the intervention is an algorithm, the trial requires its own reporting extension in addition to the core checklist.

FAIR data (for the data behind it)

Data that is findable, accessible, interoperable and reusable, which funders increasingly require and journals ask about at submission.

ISO9001:2015

Quality management (cert. H3CR9TCU20251212INDQM10N)

How the work is run, recorded and released.

Our Process

How Our Data Analysis Process Works

The first step most often determines whether the project should continue, and that is its purpose.

Step one

Assess the data

We assess size, events per variable, missingness, leakage and what the record captures. Sometimes the conclusion is that the dataset cannot answer the question.

Step two

Pre-specify the analysis

The outcome, predictors, validation strategy and performance measures are written down before the analysis starts.

Step three

Analyse and validate

The validation set is held aside from the beginning and the experiment is tracked, so the reported configuration is the one that was run.

Step four

Report for verification

Results are reported to the standard your destination uses, with code, environment and seeds handed over.

FAQs

Data and AI Services FAQs

If your question is not answered here, ask an expert — no quote is required.

Every other Pubrica service group uses this team, and keeping the work in one place keeps our methods consistent. A pooled estimate for a systematic review and one for an HTA dossier should be calculated in the same way.

Yes, although a small dataset limits what can be built. It supports a simple model with appropriate internal validation; it does not support a deep learning model with a claimed external performance.

Yes, and for identifiable data this is usually the right approach. The analysis runs under your governance, and only the output leaves your environment.

Sometimes for code and drafting, always with a named specialist accountable for the output. For anything entering a manuscript, disclosure follows the journal’s policy and we tell you what to declare.

Related services

Related Pubrica Service Groups

Most clients reach this team through one of these service groups.

Request a Free Assessment of Your Dataset

Our first assessment sometimes shows that the data supports a narrower claim than intended, and it is more economical to establish this before the analysis begins.

Get a free quote

Regulations

Check your project against this rule

  1. 1Your work
  2. 2Your details
  3. 3Send
What do you need?

Material you send is held under signed confidentiality, with access limited to the assigned team and encrypted transfer. It is not used to train anything and is not passed to third-party tools. Ask for the agreement before you send anything you would rather cover first.