Neurosyphilis with positive anti-N-methyl-D-aspartate receptor antibody: a case report

This sample case report describes a rare presentation of neurosyphilis with concurrent anti–N-methyl-D-aspartate receptor (NMDAR) antibody positivity. The case highlights the diagnostic challenge of differentiating infectious neurological disease from autoimmune encephalitis when overlapping symptoms such as cognitive impairment and seizures are present. It emphasizes comprehensive clinical evaluation, laboratory investigation, and careful interpretation of antibody findings in guiding treatment decisions. This sample demonstrates the structure, analytical depth, and clinical reasoning expected in a well-prepared neurology case report suitable for peer-reviewed publication.