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Call for papersResearch methodology

Call for Papers: Omics, big data, and bioinformatics in clinical research (BMC Medical Research Methodology)

BMC Medical Research Methodology’s collection on omics, big data and bioinformatics in clinical research covers methods for analysing high-dimensional biological data and large clinical datasets. This guide outlines topic areas consistent with that scope, fit checks, possible paper ideas and points authors should confirm before submitting.

Pubrica InsightsEditorial team, reviewed by a subject specialist
Deadline
26 February 2027
Last checked
10 November 2026
Reading time
5 min
Sources
1
Submit through the official call

Key dates

Manuscript deadline
26 February 2027
Details last checked
10 November 2026
Open the official call

About the journal

Journal
BMC Medical Research Methodology
Publisher
BMC, part of Springer Nature
Call type
Call for papers
Scope
Analysing high-dimensional biological data and large clinical datasets.
Guest editors
Listed on the official collection page
Access and fees
Open access; an article processing charge normally applies on acceptance
Originality
Original work, not under review elsewhere; confirm on the official page

Topics consistent with the call

  • Statistical methods for analysing genomic, transcriptomic, proteomic and metabolomic data
  • Approaches to integrating multi-omics data with clinical outcomes
  • Machine learning and prediction modelling using large electronic health record datasets
  • Methods for handling missing data, batch effects and measurement error
  • Simulation studies comparing high-dimensional variable selection and dimension reduction methods
  • Reproducible bioinformatics workflows and guidance for clinical research applications

Based on the published scope; the full list of themes is on the official call page.

Is your work a fit? Check before you write

  1. The manuscript makes a methodological contribution, not only reporting biological or clinical findings.
  2. The data type, dimensionality and clinical research problem are described clearly.
  3. Methods are evaluated against suitable alternatives using simulation, real data or both.
  4. Code, software or detailed settings are shared where possible to support reproducibility.
  5. The work is complete, approved by all co-authors and ready to submit before the stated deadline.

Why This Call Is a Priority Now

Clinical research increasingly draws on omics technologies and large routinely collected datasets, which raise distinct analytical challenges such as high dimensionality, heterogeneity and data quality. Choosing and applying suitable methods requires evidence on how they perform and guidance on their use. A themed collection in a methodology journal brings together new methods, comparative evaluations and tutorials, helping statisticians, bioinformaticians and clinical researchers select approaches that produce reliable and reproducible results.

Who Should Submit

Academic backgrounds

  • Biostatistics
  • Bioinformatics and computational biology
  • Health data science and machine learning
  • Genetic and molecular epidemiology
  • Clinical informatics

Institutions and sectors

  • Universities and research institutes
  • Hospital research and health data departments
  • Pharmaceutical and biotechnology companies
  • Genomics and health data infrastructure organisations

Article types commonly published in BMC Medical Research Methodology

  • Methodology articles describing new or adapted methods
  • Simulation studies comparing the performance of methods
  • Empirical studies evaluating methods on real data
  • Tutorials and guidance on applying methods

What the Editors Typically Value

  1. New or adapted methods that address a specific challenge of high-dimensional clinical data.
  2. Neutral, well-designed comparisons of existing methods on realistic simulated and real data.
  3. Open, reproducible software or workflows with clear documentation.
  4. Tutorials that make complex analytical methods accessible to clinical research teams.

Paper Ideas You Could Develop

Comparison of multi-omics integration methodsA simulation and real-data study comparing multi-omics integration methods for predicting a clinical outcome, reporting accuracy, stability and interpretability.
Batch effect correction in clinical cohortsA methodology article proposing an adapted batch correction approach for omics data collected across clinical sites, evaluated on a public dataset.
Tutorial on prediction with health recordsA tutorial guiding clinical researchers through developing and validating prediction models from large electronic health record data, with reproducible code.

Your Plan to the Deadline

A suggested schedule working back from 26 February 2027. Adjust it to the stage your work has reached.

  1. By 12 Jan 2027

    Open the official collection page and the BMC Medical Research Methodology submission guidelines; confirm the scope, article types and guest editors.

  2. By 26 Jan 2027

    Write a one-paragraph statement of your research question, design and the contribution your paper makes to the collection.

  3. By 5 Feb 2027

    Complete the analysis and agree the key findings, figures and tables with your co-authors.

  4. By 16 Feb 2027

    Draft the full manuscript to the BMC Medical Research Methodology article type and the relevant reporting guideline.

  5. By 21 Feb 2027

    Circulate the draft to co-authors and an independent reader; revise for clarity, accuracy and completeness.

  6. By 24 Feb 2027

    Complete final checks: formatting, references, declarations, data availability statement and cover letter.

  7. By 26 Feb 2027

    Submit through the journal’s online system, selecting the collection, after re-checking the official call page.

What you gain from publishing here

  • Publication in BMC Medical Research Methodology, reaching readers working on this topic.
  • A themed collection that groups your paper with related work.
  • Editorial and peer feedback that can strengthen the work, whatever the decision.
  • A peer-reviewed output for your CV, thesis or grant reporting.

What happens after you submit

  1. Submission: upload through the BMC Medical Research Methodology online system and select the collection.
  2. Editorial screening: the editors check fit with the collection; papers outside its scope may be returned without review.
  3. Peer review: suitable papers are sent to reviewers under the journal’s review model.
  4. Revision and decision: respond to each reviewer comment and keep a record of the changes.
  5. Production: accepted papers move to proofs and open access publication, with the article processing charge set out by the publisher.

What the Collection Is Looking For

The collection seeks methodological work on analysing high-dimensional biological data and large clinical datasets. Consistent with BMC Medical Research Methodology’s remit, suitable submissions are likely to include methodology articles, simulation studies comparing methods, empirical evaluations on real data and tutorials. Work that addresses a clearly defined analytical problem, evaluates performance transparently and supports reproducibility is likely to be of most interest.

Read the call itselfThis guide summarises the call. Open the official collection page before you plan a submission, and record the date you checked it and the guest editors listed.Open the official call

Expert help

How Pubrica Can Help With This Submission

Pubrica’s subject specialists can review, write, edit, format and prepare your manuscript for this call, planned back from the deadline. You remain the author of your work.

Biostatistics and statistical programmingStatistical analysis plans, analysis, simulation code and statistical review of results. Original research article writingManuscript writing from your data, structured to the journal’s article type and reporting guideline. Manuscript editingLanguage and technical editing to prepare the manuscript for submission. Journal formattingFormatting of the manuscript, references, figures and tables to the journal’s guidelines. Cover letterA cover letter that explains how the manuscript fits the collection and the journal’s scope. Journal submissionPreparation of submission files and completion of the journal’s online submission system.
Go to the official call

FAQs

Questions Authors Ask

The published deadline is 26 February 2027. Collections can close early or be extended, so confirm the date on the official call page before you plan your submission.

The guest editors are listed on the official collection page. Check their research interests, as they help to judge whether your manuscript fits the collection.

A study reporting mainly substantive findings is unlikely to fit a methodology collection. It may be suitable if the main contribution is a new or improved analytical approach, with the findings used as illustration. Authors should confirm the scope on the official call page.

BMC journals publish articles open access, and an article processing charge normally applies on acceptance. Check the journal’s fees and funding page, and whether your institution has an agreement that covers the charge, before you submit.

Sources

  1. BMC Medical Research Methodology. (2026). Omics, big data, and bioinformatics in clinical research [Collection call for papers]. BMC, part of Springer Nature. Retrieved 10 November 2026, from https://link.springer.com/collections/cgahddgagc

How to cite this page

Pubrica Insights. (2026). Call for Papers: Omics, big data, and bioinformatics in clinical research (BMC Medical Research Methodology). Pubrica. https://pubrica.com/insights/calls-and-conferences/omics-big-data-and-bioinformatics-in-clinical-research/

  • Omics
  • Big data
  • Bioinformatics
  • Machine learning
  • Research methodology

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Omics, big data, and bioinformatics in clinical research (BMC Medical Research Methodology)Deadline 26 February 2027

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