Individual Participant Data

Clinical trials include a large number of people, and data is gathered on each one of them. Individual Participant Data is the name given to this information (IPR). This information may include participant demographics, vital sign measures, medical history, laboratory and diagnostic findings, adverse events, therapy details, and clinical outcomes before and after treatment.

It is used in a variety of meta-analysis research, according to IPR. Individual participant data (IPD) meta-analysis refers to collecting and analyzing participant data from several studies, unlike average meta-analysis, which examines aggregated data from various sources such as publications or authors. The key benefit is that it is not overly reliant on manuscript data and publishing qualities because the availability of raw data allows for greater flexibility in analysis and a better understanding of heterogeneity and its effective relationships.

IPD meta-analysis can be performed in either one or two steps. Meta-analyses of IPD showed it useful in investigations of cardiovascular disease and cancer, diabetes, infections, mental health, dementia, epilepsy, hernia, and respiratory illness. The process requires more time and money than a traditional systematic review procedure. Data on IPD reviews may be found at cochrane.org.

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