Syncope from Dynamic Left Ventricular Outflow Tract Obstruction Simulating Hypertrophic Cardiomyopathy in a Patient with Primary AL-Type Amyloid Heart Disease
Simplified Abstract
Sample Work
Cardiac amyloidosis can rarely mimic hypertrophic cardiomyopathy (HCM) through asymmetric septal hypertrophy and dynamic left ventricular outflow tract (LVOT) obstruction. Although syncope in amyloidosis is commonly attributed to arrhythmias, conduction abnormalities, or autonomic dysfunction, dynamic LVOT obstruction may also be an important cause. This case highlights the role of provocative echocardiographic assessment in identifying LVOT obstruction as a potential mechanism of syncope in patients with primary AL cardiac amyloidosis.
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