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Bioinformatics Support for Scientific Research and Publication 

Pubrica’s team of bioinformatics experts specializes in analyzing complex biological data, particularly from genomic, proteomic, and other omics studies, tailored specifically for medical, life science, and healthcare research. Our sophisticated bioinformatics capabilities ensure the generation of insightful scientific publications. 

  • Data Management and Organization: Our bioinformatics professionals are skilled in handling and structuring vast omics datasets, ensuring they are clean, well-organized, and primed for detailed analysis. This precise data management is crucial for addressing specific biological research questions with accuracy.
  • Customized Bioinformatics Analysis: Tailor the scope of your bioinformatics projects to meet specific research objectives and budget requirements. Our personalized approach not only enhances the relevance of your research but also enables deep and meaningful analysis using advanced bioinformatics tools and methods.
  • Advanced Bioinformatics Programming: Benefit from our robust experience in bioinformatics programming for scientific publications. Our team conducts comprehensive analyses, employing both established and cutting-edge bioinformatics techniques. This includes genomic sequence analysis, protein structure prediction, and complex trait association studies. Our methods allow us to effectively interpret biological data, resulting in clear and insightful visualizations like phylogenetic trees, heat maps, and gene expression profiles, which facilitate informed decision-making in biological research and clinical applications.

Pubrica ensures that your research is supported by accurate bioinformatics analysis and sophisticated data handling, contributing significantly to advancements in the scientific community. 

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Bioinformatics Services that we undertake.

Pubrica offers a comprehensive suite of bioinformatics services tailored to the life science and medical sectors, supporting researchers in unraveling complex biological data and advancing scientific discoveries.  

Here’s a detailed look at the specific bioinformatics services Pubrica provide: 

We specialize in sequencing data analysis, including whole-genome sequencing, exome sequencing, and targeted sequencing. Our services help in identifying genetic variations, understanding genetic predispositions to diseases, and exploring genomic influences on drug responses.
  • What tools are used in Genomic Data Analysis at Pubrica?
    • We use a variety of bioinformatics tools such as BWA for alignment, GATK for variant calling, and PLINK for genetic association studies, along with specialized software like UCSC Genome Browser for visualization.
  • What variables are considered in Genomic Data Analysis?
    • Variables include genetic variants (SNPs, indels), coverage depth, genotype quality, population stratification, and phenotypic data, essential for accurate genomic interpretation.
  • What type of analyses are conducted in Genomic Data Analysis?
    • Analyses include whole-genome sequencing analysis, SNP calling, comparative genomics, and linkage disequilibrium analysis, aimed at uncovering genetic associations and mutations.
  • What compliances are followed to ensure publication in peer-reviewed journals?
    • We adhere to FAIR principles (Findability, Accessibility, Interoperability, and Reusability) and follow guidelines set by consortia such as the Human Genome Organisation (HUGO) to ensure that genomic data handling and reporting are of the highest standard.

Our expertise extends to the analysis of proteomic data, which includes protein identification, quantification, and post-translational modification analysis. These services are crucial for understanding disease mechanisms and discovering new therapeutic targets.

  • What tools are used in Proteomic Analysis at Pubrica? 
    • Tools like MaxQuant for quantitative proteomics, Mascot for protein identification, and Cytoscape for network analysis are employed to analyze proteomic data comprehensively. 
  • What variables are considered in Proteomic Analysis? 
    • Considerations include protein abundance, post-translational modifications, protein-protein interactions, and sample preparation variables, which influence the outcome of proteomic studies. 
  • What type of analyses are conducted in Proteomic Analysis? 
    • We conduct protein quantification, identification of modifications, interaction mapping, and functional enrichment analysis, providing insights into protein dynamics and functions.
  • What compliances are followed to ensure publication in peer-reviewed journals? 
    • Compliance with MIAPE (Minimum Information About a Proteomics Experiment) standards and PRIDE database guidelines for proteomics data ensures that our analyses meet journal requirements for reproducibility and transparency. 

We offer services in RNA sequencing data analysis to study gene expression changes under various conditions. This includes differential gene expression analysis, isoform identification, and non-coding RNA analysis.

  • What tools are used in Transcriptomic Analysis at Pubrica? 
    • We utilize RNA-seq tools such as STAR for alignment, Cufflinks for transcript assembly, and DESeq for differential expression analysis, among others, to analyze transcriptomic data. 
  • What variables are considered in Transcriptomic Analysis? 
    • Variables include read counts, gene expression levels, biological replicates, and experimental conditions, crucial for robust transcriptomic analysis. 
  • What type of analyses are conducted in Transcriptomic Analysis? 
    • Our analyses cover differential gene expression, alternative splicing events, gene ontology, and pathway analysis to explore regulatory mechanisms and gene functions.  

Our services include the analysis of metabolomic data to identify key metabolic changes associated with diseases. This helps in understanding disease pathways and potential metabolic markers.

We provide integrative analysis services that combine data from genomics, transcriptomics, proteomics, and metabolomics. This holistic approach offers deeper insights into the molecular mechanisms underlying diseases and enhances biomarker discovery. 

Our services include protein structure prediction, molecular modeling, and simulation to help understand the structure-function relationships of biomolecules, which are essential for drug design and understanding protein-ligand interactions. 

We conduct phylogenetic analysis and comparative genomic studies to understand the evolutionary relationships among species, which can shed light on the genetic basis of diseases. 

We develop customized bioinformatics software and pipelines tailored to the specific needs of your research projects, ensuring efficient data processing and analysis.

What compliances are followed to ensure publication in peer-reviewed journals?

We ensure compliance with standards such as the Minimum Information for the publication of Quantitative Real-Time PCR Experiments (MIQE) and recommendations by the ENCODE project, facilitating the integrity and reproducibility of transcriptomic data.

These comprehensive answers highlight Pubrica’s commitment to utilizing advanced bioinformatics tools, considering key variables, conducting thorough analyses, and following strict compliance standards to support the publication of your research in respected scientific journals.

These services are designed to enable breakthroughs in understanding complex biological systems and advancing medical research, ensuring that your projects are equipped with the latest in bioinformatics technology and expertise.

How Do Bioinformatics Services & Solutions Work at Pubrica?

Pubrica’s comprehensive suite of bioinformatics services provides specialized support to researchers and clinicians, ensuring that your research meets the stringent standards necessary for publication in top medical and scientific journals. 

End-to-End Bioinformatics Services

At Pubrica, our Bioinformatics Services are meticulously designed to handle complex biological data, facilitating groundbreaking discoveries in the fields of healthcare, medical, and life science research. Here’s a detailed look at our process, from initial data handling to comprehensive analysis and compliance assurance:

The process starts with the systematic collection and detailed annotation of biological data, which is crucial for subsequent analyses. This includes genomic, proteomic, transcriptomic, and metabolomic data, ensuring they are accurately annotated and categorized according to the specific needs of the project. 

With the annotated data ready, our team of bioinformatics experts develops custom algorithms tailored to address the unique challenges and objectives of each project. This might involve adapting existing algorithms or designing new methods to analyze and interpret the biological data effectively. 

We ensure strict adherence to relevant scientific standards and ethical guidelines, including those specific to genomic data like the Genomic Data Sharing Policy (GDS) and other relevant FAIR principles. Compliance is critical to maintaining the integrity and reliability of the data handling and analytical processes. 

Our bioinformatics models are rigorously tested and validated to ensure accuracy and robustness. This includes using various computational techniques to analyze and validate the data across different scenarios, ensuring the models provide reliable and replicable results. 

After model validation, we use the models to generate detailed insights, which are crucial for scientific discoveries and clinical applications. We provide extensive reports and visualizations, interpreting the data in a way that is understandable and actionable, turning complex datasets into clear scientific knowledge. 

We provide comprehensive deliverables that include all data analyses, detailed documentation of methodologies, algorithms used, and the insights generated. Support for implementation of these findings into practical applications is also provided, ensuring the research can be effectively applied in real-world settings. 

Pubrica guarantees the quality and scientific rigor of our bioinformatics analyses and offers ongoing support after project completion. This includes updates and refinements to the analyses as new data becomes available or as research objectives evolve, ensuring continued relevance and accuracy. 

Our team of bioinformatics experts ensures that all analyses comply with relevant guidelines, applying rigorous methods to enhance the precision and relevance of your results.

What are the different compliance guidelines Pubrica follows in bioinformatics analysis?

Pubrica adheres to guidelines such as FAANG (Functional Annotation of Animal Genomes) and MIAME (Minimum Information About a Microarray Experiment), ensuring that our bioinformatics analyses maintain the reliability and integrity necessary for high-impact results. 

We meticulously adhere to the reporting structures required by journals, including detailed descriptions of methodologies (data sourcing, selection criteria, predefined computational analyses, quality appraisal of data, and validity assessment), comprehensive data analyses, and insightful discussions of the results.

Reports are structured to include comprehensive methodologies, such as the criteria for data inclusion, bioinformatics tools and tests used, model validation techniques, and a robust discussion of the results, ensuring clear communication and replicability of research. 

Preparation of essential documentation for bioinformatics data management, including the setup of data retrieval systems, database utilization for advanced analytics, and establishing robust inclusion and exclusion criteria for data analysis.

Assistance with data sourcing, advanced preprocessing, and analytical characterization of biological data to enrich the depth and impact of your research findings. 

Enhancement services include sophisticated data preprocessing, application of advanced computational models, and detailed data visualization techniques to deepen insights and enhance the interpretability of the results.

Comprehensive support including journal selection, submission process, cover letter preparation, response to editorial comments, resubmission, and follow-up with editorial teams, ensuring smooth progress towards publication. 

Detailed analysis of data integrity, including validation checks and error analysis, ensuring the high quality and reliability of the bioinformatics models and findings. 

A committed project coordinator to assist with all queries related to your bioinformatics analysis or modeling project, providing seamless and personalized support.

This tailored approach ensures that your bioinformatics research is not only scientifically rigorous but also utilizes the latest in computational technology to provide insightful and actionable results. 

Bioinformatics Services Sample Work

our editors’ process to see the benefits you get from our services.

What our client says About us

RAISSA

BIOMEDICAL RESEARCHER, UK
Pubrica's contribution and commitments have been crucial to our trials success and our products clearance. I now consider them part of the clinical team and trust them at every clinical development stage

OLAF

BIOMEDICAL RESEARCH. DUBAI
I enjoyed collaborating with the pubrica team and consider using its services for future clinical studies and recommend their services to other companies.

Frequently Asked Questions

We are with you the whole nine yards. In this section, we answer the tough questions. For any information, contact us meanwhile, here are some of those queries
We offer complete Bioinformatics services for proteomic and genomic data for a comprehensive range of bioinformatics services, including research, bioinformatics software, bioinformatics tools, and bioinformatics databases services.

We have disease-specific research, cost-effectiveness research, and resource utilization research. Please see https://pubrica.com/services/bioinformatics/ for additional information on how to choose a detailed research area plan.

We need a clear and specific Domain area to choose Bioinformatics Services. Take, for example, drug development. Genomic and proteomic research are two areas of interest. Proposal for Research with clarity a rough outline, Please provide 2-3 significant references, data collecting feasibility, and university guidelines, as well as the following information: your qualifications, industry, and education, areas of your interest, supervisory skills, and university interest, as well as a novel approach based on your research and areas of interest.

Pubrica’s hires only experienced and certified professionals from European and UK bases. All of our researchers and scientists for bioinformatics have at least five years of writing experience. Each bioinformatician has their specialization; it supports us in assigning the most qualified writer for your discipline. We guarantee that you will receive just subject expertise, i.e., every research proposal order will include only the appropriate research background.

Pubrica hires only experienced and qualified experts from Europe and the United Kingdom. All of our bioinformatics researchers and scientists have at least five years of writing experience. Each bioinformatician has the expertise, which allows us to assign the most qualified researchers to your discipline. We guarantee that you will receive just subject expertise, i.e., every research proposal order will include only the appropriate research background.

Yes, at research Support, our motto is to work hands-on with clients. So we exceed their expectations of full-fledged research services for bioinformatics domains. We guarantee 100% research satisfaction. Call us now to get a quote.

Bioinformatics, in combination with big data analytics, provides relevant techniques for deciphering the massive dataset. It allows for earlier disease detection and treatment, resulting in significant cost savings.

Bioinformatics as a Service gives the experience, software, tools, and results you need to accomplish and plan and improve your research.

Our bioinformaticians have created a variety of models to meet the demands of our clients, ranging from simple cost calculations to estimating the costs of treatments and adverse events too complicated to examine the economic complications. Budget impact models are used the new formulary cost-utility.

Bioinformatics is increasingly being utilized for a wide range of other critical activities, including gene variation and expression analysis, gene and protein structure and function analysis and prediction, gene regulation network prediction and detection, and simulation environments.

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