Bioinformatics

Biological sequence arrangement and validation

Pubrica’s Bioinformatics team supports identifying a specific disease and target selection, providing a summary and analysis of the relevant information in a given area.

Sequence analysis is the process of exposing a DNA, RNA, or peptide sequence to bioinformatics analysis through various analytical techniques to understand better its properties, function, structure, or evolution. Other techniques have been applied, including sequence alignment searches against biological databases. Active sites, post-translational modification sites, gene topologies, reading frames, intron and exon distributions, and regulatory regions are all illustrations of sequence intrinsic features. In sequence analysis, the genetic marker to identify sequence differences and variations such as point mutations and single nucleotide polymorphism (SNP) must be discovered.


There are three levels of sequencing present in sequence analysis; The sequencing technique and the dideoxy sequencing approach are examples of first-generation sequencing techniques. Massively parallel sequencing of genes with short read lengths of DNA is a feature of second-generation sequencing technologies. The short-length sequences then necessitate a lot of assemblies. Assembly is challenging in complex areas of the genome, such as those with a high content of repetitive sequences. Single-molecule real-time sequencing is used in third-generation sequencing methods (SMRT). Pacific Biosciences was the first company to develop and market this technology (Pac Bio). Pac Bio sequencing has been demonstrated to be particularly useful for sequencing through repetitive regions with long repeats.

Our Bioinformatics Comprehensive Services

  • Demonstrate your knowledge of the key ideas and concepts in your topic
  • Evaluate previous research studies
  • Assist you in believing that your field of study is worthwhile
  • Describe your theoretical and practical framework in detail.
  • Examine prior study approaches to avoid making the same mistakes as earlier researchers
  • Cite other authors to support your work
Research
 

Types of Bioinformatics: We undertake different types of Gene prediction for Exon prediction, Non-Coding regions and ab-initio methods for gene prediction analysis.

 
 

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Frequently asked questions

We are with you the whole nine yards. In this section, we answer the tough questions. For any information, contact us via +91-9884350006 meanwhile, here are some of those queries

11. What is Bioinformatics Database?

Solve an issue with computational modeling. A bioinformatics solution frequently included in the following steps is: Compile statistical information from biological data. Essentially generate a computational model. A computing algorithm is sorely tested and evaluated.

22. What types of Databases are used in Bioinformatics?

Bioinformatics has benefited evolutionary study by allowing researchers to compare DNA sequences, exchange information, anticipate potential evolution, and classify complex evolutionary processes. Overall, bioinformatics has opened up a world of possibilities in genomics and targeted gene therapy.

33. What is the Primary database in Bioinformatics?

We make sure the safety and protection of your data. We are enthusiastic about signing a non-disclosure agreement (NDA if need be to ensure the security of your data).

44. What are the goals of the Bioinformatics Database?

Disease-specific research, topic selection, target identification, ligand discovery, cost-effectiveness research, and resource utilization have all been aspects we're researching into. Additional information on how to choose a detailed study area plan can be found at https://pubrica.com/services/bioinformatics/.

55. Which Bioinformatics Database is mainly used in Sequence retrieval?

The Bioinformatics pathway focuses on three study areas: computational biology and bioinformatics; Genetics and genomics are often used interchangeably and system biology.

 
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