Homology Modeling
Pubrica’s provide our researchers for Bioinformatics services & analysis service also include drug development, Molecular Docking, Process of modeling development, Phylogenetic analysis, Molecular format conversion and Protein structure visualization of the relevant information in a given area. Our team protects your private confidentiality of research.
Homology modeling has developed into a critical element in structural biology, helping to bridge the gap between known protein sequences and empirically established structures. Fully automated workflows and servers simplify and speed the homology modeling process, allowing even non-computational experts to build credible protein models and quickly access modeling results, visualization, and interpretation. Although when determined under comparable conditions, two proteins with a high level of sequence identity and highly similar secondary and tertiary structure (identical "folds") will not have precisely identical backbone conformations. To at least this extent, a homology model can be predicted to diverge from the simple structure. The root means square deviation (RMSD) of alpha carbons or RMSD positions is used to quantify overall changes in protein backbone structures. When the RMSD of a model is within the spread of deviations found for experimental structures demonstrating a comparable sequence identity level as the target and template sequences, it can be termed accurate enough or as exact as you can get.
Our comprehensive Bioinformatics Software services
Types of Bioinformatics: We undertake different types of Homology Modeling for Fragment assembly, Segment matching, Satisfaction of spatial restraints and Structural comparison methods for your particular work.
Wide range of Sources: NCBI, BLAST, Pubmed, Pubmed Nucleotide, Pubmed Protein, Pubmed Gene, Pubmed Sequence.
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Pubrica Offerings
Pubrica provides comprehensive bioinformatics research work publishing assistance for various publications, journals, and books. With our writing services, you can now turn your ideas into Project writing, Proposal writing, Research Writing, Thesis writing and Manuscript writing. Science, Technology, Engineering, and Mathematics (STEM) experts with a therapeutic background. It is now simple to publish a research work or obtain regulatory drug approval. With Pubrica's help, you can save time and money.
Frequently asked questions
We are with you the whole nine yards. In this section, we answer the tough questions. For any information, contact us via +91-9884350006 meanwhile, here are some of those queries
To predict the secondary and tertiary structure of a protein molecule, a variety of software is available. E.g. Autodock is a suite of automated docking studies; it was mainly used to analyze the molecular docking of target protein and ligand.
Our service fees are determined by the requirements that are submitted to us. If you want to learn more about it, go through https://pubrica.com/services/bioinformatics/. We'll contact you as soon as possible.
Bioinformatics analysis speeds up drug target identification and candidate screening and refining, but it can also help characterize adverse effects and anticipate drug resistance.
Sequence similarity searches, multiple sequence alignments, domain identification and characterization, secondary structure prediction, solvent accessibility prediction, automatic protein fold recognition, three-dimensional model construction to atomic detail, and model validation can all be used to predict protein structure using bioinformatics..
RasMol is a molecular graphics tool that allows you to see proteins, nucleic acids, and small molecules in 3D structure 2D structure visualization. It shows the ball and stick model, molecular surface, ribbon model etc.
