Mean and Mean difference are the two key statistical measures used in the statistical analysis. Both are essential for meta-analysis as well. Mean and Mean difference are used for the interpretation of a large set of values into a single number which explains the heterogeneity and variation among the individual values. However, one of a common challenge in meta-analysis is the unavailability of this data (mean and standard deviation).
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Meta Analysis
SMDs, often referred to as effect sizes, can be interpreted using commonly accepted guidelines, primarily derived from social science research. One widely used scale (Cohen, 1988) suggests:
Other variations exist, such as:
Cochrane Handbook for Systematic Reviews of Interventions. (2011). 12.6.2 Re-expressing SMDs using rules of thumb for effect sizes. The Cochrane Collaboration. Retrieved from