Mean and Mean difference are the two key statistical measures used in the statistical analysis. Both are essential for meta-analysis as well. Mean and Mean difference are used for the interpretation of a large set of values into a single number which explains the heterogeneity and variation among the individual values. However, one of a common challenge in meta-analysis is the unavailability of this data (mean and standard deviation).
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Meta Analysis
Meta-analysis is one of the methods of systematic review. It is the quantitative methods of performing the literature review that helps to minimize the data not justified by subjective interpretation. It considers studies with the same outcome to draw conclusive evidence summarizes statistics of individual studies and combines them to derive an answer for hypothetical questions. The number of studies and a number of samples within the study is crucial for a confident answer. The meta-analysis is usually regarded as a true effect when the number of studies is more. Reducing the size can significantly reduce the time needed for review.[1]
Currently, there is no rule describing the minimal studies required to do a meta-analysis. But the fewer studies are not enough to derive conclusive evidence for the hypothesis.