Mean and Mean difference are the two key statistical measures used in the statistical analysis. Both are essential for meta-analysis as well. Mean and Mean difference are used for the interpretation of a large set of values into a single number which explains the heterogeneity and variation among the individual values. However, one of a common challenge in meta-analysis is the unavailability of this data (mean and standard deviation).

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Meta Analysis

Q:How to estimate Standard Deviation be estimated with Q1, minimum, median, Q3, and maximum values?

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Lou et al. stated a alteration of Bland’s method to calculate Standard Deviation based on the same principles, by using Formulas 13 and 14 for more precise estimation.

bland method

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