MI help in the prediction of COVID-19 diagnosis

COVID-19 is now causing significant death and morbidity around the world. There is a scarcity of information about heart damage. To assess cardiovascular damage in COVID-19 patients and establish the relationship between high-sensitivity cardiac-specific troponin T (hs-cTnT) and N-terminal pro-B-type natriuretic peptide (NT-proBNP) and COVID-19 severity. The first instances of pneumonia of unknown origin were reported in Wuhan, China, in December 2019. What is now known as COVID-19 illness was caused by a new coronavirus known as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) because it resembled the earlier SARS virus? Spain has the largest number of illnesses and the highest number of recorded fatalities per million populations.

Coronaviruses are known to impact the cardiovascular system, and preliminary research indicates that the rates of complications and death from COVID-19 are greater in individuals who had pre-existing cardiovascular risk factors or cardiovascular illness. Furthermore, two investigations in two Chinese cohorts found that myocardial damage and cardiovascular risk factors were related to a poorer outcome in COVID-19 patients. It has been suggested that the virus might induce cardiac damage, although data on this is limited, and the clinical and prognostic implications are unknown. Troponin has been used to assess the amount of cardiac damage, but measuring the level of N-terminal pro-B-type natriuretic peptide (NT-proBNP) on the admission of COVID-19 patients may assist in stratifying better the risk of in-hospital death or mechanical ventilation (MV).

The goal of this study was to see how accurate it was to predict short-term mortality or MV by integrating cardiac damage information from high-sensitivity cardiac-specific troponin-T (hs-cTnT) with NT-pro-BNP assessed on entry in COVID-19 participants.

References

Calvo-Fernández, Alicia, et al. “Markers of myocardial injury in the prediction of short-term COVID-19 prognosis.” Revista Española de Cardiología (English Edition) 74.7 (2021): 576-583.