Turn Evidence Into Impact, Research Into Results With Our Health Economics & Outcomes Research (HEOR) Expertise
- 1,500+ HEOR projects completed across cost-effectiveness, real-world evidence, and patient-reported outcomes.
- Multidisciplinary team of economists, statisticians, epidemiologists, and medical writers.
- Exclusive focus on researchers preparing manuscripts, dissertations, publications and policy makers.
- Proven track record in supporting successful submissions to peer-reviewed journals.
- Global expertise across multiple therapeutic areas and healthcare systems.
- Compliance with international guidelines (CONSORT, SPIRIT, ICMJE, HTA standards).
- Evidence tailored for publication as well as funding and market access success.
Our proven track record ensures that your research demonstrates both scientific credibility and economic value, increasing its potential for peer-reviewed journal acceptance and funding success.
What We Do
Economic evaluation in healthcare & Cost-Effectiveness Analysis
We develop robust economic models that evaluate treatment costs, value for money, and healthcare resource allocation. Our cost-effectiveness analysis services support HTA submissions, payer negotiations, and peer-reviewed publications.
Real-World Evidence (RWE) Generation
Pubrica’s experts analyze clinical, observational, and claims data to generate real-world evidence. These insights help healthcare providers, regulators, and payers make informed decisions that enhance patient outcomes and value-based care.
Systematic Literature Reviews (SLRs) & Meta-Analyses
We conduct systematic literature reviews and meta-analyses to synthesize published data. These outputs strengthen clinical guidelines, health technology assessments (HTAs), and product positioning in global healthcare markets.
Patient-Reported Outcomes (PROs)
Our team designs and validates patient-reported outcomes studies to capture patient perspectives on quality of life, treatment satisfaction, and therapy benefits. PRO evidence supports regulatory approval and high-impact journal publication.
Market Access & Reimbursement Strategy
We create market access strategies and reimbursement dossiers tailored to payer requirements. Our HEOR experts align evidence with national and international HTA frameworks, helping products secure funding and adoption.
Comparative Effectiveness Research (CER)
Pubrica delivers comparative effectiveness research that evaluates alternative interventions and therapies. CER evidence guides clinical decision-making, policy development, and formulary inclusion, ensuring your research is impactful and relevant.
Health Technology Assessment (HTA) Support
Our experts offer end-to-end HTA submission support services, including evidence synthesis, modeling, and dossier preparation. We align research outputs with international HTA frameworks, ensuring your study meets the requirements of regulators, payers, and healthcare authorities.
Modeling Approaches (Advanced Methods)
Pubrica specializes in advanced HEOR modeling approaches, including Markov models, decision-analytic models, and survival models. These methods provide a robust framework to evaluate long-term clinical and economic outcomes. Our customized HEOR models support clinical development, pricing strategies, and value demonstration for publication.
Who We Serve
At Pubrica, our Health Economics & Outcomes Research (HEOR) services support a diverse range of stakeholders across healthcare, life sciences, academia, and policy, delivering robust, evidence-based insights for decision-making, publication, and market access.
Pharmaceutical & Biotechnology Companies
We partner with pharmaceutical and biotech companies to demonstrate product value, cost-effectiveness, and market readiness. Our experts provide HEOR support for clinical development, HTA submissions, and pricing strategies, helping accelerate regulatory approval and market access success.
Medical Device Manufacturers
Pubrica supports medical device companies with economic evaluations, budget impact analyses, and real-world evidence generation. We demonstrate the clinical and economic value of devices and diagnostics, ensuring alignment with regulatory requirements, payer expectations, and reimbursement frameworks.
Healthcare Providers & Hospitals
We assist hospitals and healthcare providers in evaluating treatment strategies, comparative effectiveness, and patient outcomes. Our HEOR consulting services optimize resource allocation, cost management, and value-based care delivery, helping institutions achieve better outcomes at lower costs.
Payers & Insurance Companies
Pubrica works with payers, insurance, and reimbursement agencies to provide budget impact models, cost-effectiveness evidence, and coverage decision support. Our health economics consulting ensures that reimbursement policies are grounded in robust data and real-world insights, enabling sustainable healthcare financing.
Policy Makers & HTA Agencies
We collaborate with policy makers and HTA agencies to generate evidence that informs reimbursement decisions, treatment guidelines, and health policies. Our HTA submission support services align research with national and international assessment frameworks, enabling transparent and evidence-based healthcare decision-making.
Academic Researchers & Institutions
Pubrica supports academic researchers and universities in producing publication-ready HEOR studies, systematic literature reviews, and meta-analyses. Our experts help transform data into impactful manuscripts for peer-reviewed journals, ensuring greater visibility, credibility, and contribution to global evidence generation.
Contract Research Organizations (CROs)
We partner with CROs to provide independent HEOR study design, data analysis, and economic modeling support. Our collaboration strengthens clinical trial evidence packages and ensures methodological rigor in multinational studies.
Non-Governmental Organizations (NGOs) & Public Health Bodies
For global health and non-profit organizations, Pubrica develops epidemiological models, cost-effectiveness studies, and health policy analyses. Our evidence supports program evaluation, donor funding justification, and large-scale public health decision-making.
Our Approach
At Pubrica, we combine scientific rigor with real-world insights to deliver meaningful Health Economics & Outcomes Research (HEOR) solutions. Our approach is built on:
Evidence-Based Methodologies
Patient-Centred FocusWe integrate patient-reported outcomes (PROs), patient journey mapping, and quality-of-life assessments, ensuring healthcare decisions reflect what matters most to patients.
Collaborative EngagementOur team works closely with clients, payers, clinicians, and policy makers to align HEOR research with stakeholder needs and expectations.
Global Standards & ComplianceAll research adheres to ISPOR, NICE, ICER, and HTA body guidelines, ensuring credibility, regulatory acceptance, and successful HTA submissions across global markets.
Data-Driven Insights Leveraging real-world data, clinical trial results, and predictive modeling, we transform complex healthcare data into actionable strategies for decision-making.
Value DemonstrationWe translate evidence into clear value stories that support market access, reimbursement approvals, and peer-reviewed publications, driving value-based care initiatives.
How Our Health Economics & Outcome Research Service Works
Our Step-by-Step Process for Evidence-Based and Actionable Insights
At Pubrica, our Health Economics & Outcomes Research (HEOR) services follow a structured, evidence-driven process designed to deliver scientific rigor, real-world insights, and actionable outcomes. From early strategy development to advanced health economic modeling and regulatory-compliant reporting, every project is aligned with global healthcare and HTA standards.
Understanding Your Needs
We begin by analyzing your product profile, therapeutic area, and market access challenges, defining clear HEOR objectives aligned with publication, funding, and reimbursement goals.
Data Collection & Validation
We collect and validate data from clinical trials, real-world evidence (RWE), patient-reported outcomes (PROs), healthcare resource utilization studies, and large healthcare databases.
Model Development & Analysis
Our experts apply advanced health economic models including cost-effectiveness analysis, budget impact analysis (BIA), cost-utility analysis, and comparative effectiveness research (CER) to assess value.
Evidence Synthesis
We integrate findings through systematic literature reviews (SLRs), meta-analyses, and evidence synthesis frameworks to support HTA and payer submissions.
Value Communication
We transform complex evidence into clear value dossiers, payer submissions, health technology assessments, and peer-reviewed publications tailored to global stakeholders.
Regulatory & Market Alignment
All outputs are aligned with international HEOR guidelines (ISPOR, NICE, ICER, and HTA bodies), ensuring credibility, acceptance, and strong market access strategies.
Actionable Insights Delivery
We deliver evidence-driven recommendations that support coverage decisions, reimbursement strategies, and value-based healthcare initiatives.
Accelerate Your Health Economics & Outcome Research Modeling with Pubrica
Pubrica’s HEOR modeling services deliver comprehensive analysis, refinement, optimization, and quality assurance, ensuring precision and reliability. Our experts specialize in cost-effectiveness models, budget impact analyses, Markov and decision-analytic models, and other advanced frameworks to generate robust insights. With scientifically validated models, we help stakeholders drive strategic healthcare outcomes, value demonstration, and informed economic decision-making.
Our Compliance and Guideline Standards
International Guidelines
We align with ISPOR, CHEERS 2022, PRISMA (for systematic reviews), and HTA body requirements including NICE (UK), CADTH (Canada), ICER (US), HAS (France), and IQWiG (Germany).
Regulatory Compliance
Our deliverables adhere to FDA, EMA, and other regional authority guidelines, ensuring acceptance in submissions, approvals, and market access strategies.
Ethical Standards
We follow Good Publication Practice (GPP), ICMJE, and data transparency requirements to guarantee ethical integrity and scientific credibility in all research outputs.
Data Privacy & Security
We strictly comply with GDPR (EU), HIPAA (US), and other local data protection regulations, safeguarding patient information and sensitive healthcare data.
Health Economics & Outcome Research Sample Work
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Testimonials
"Pubrica’s HEOR team provided exceptional support in developing a cost-effectiveness model for our oncology research. Their attention to regulatory compliance and scientific accuracy made our publication in the Journal of Health Economics seamless."
— Dr. Maria Gonzales
Health Economist, Spain
"With Pubrica’s HEOR expertise, we were able to design robust patient-reported outcome studies that met international guidelines. Their guidance elevated the credibility of our research findings, leading to acceptance in the Pharmacoeconomics journal."
— Dr. Akira Tanaka
Clinical Research Scientist, Japan
"The economic modeling and systematic reviews prepared by Pubrica exceeded our expectations. Their team combined technical depth with practical recommendations that directly supported our reimbursement submissions and a publication in the International Journal of Technology Assessment in Health Care."
— Prof. Ananya Iyer
Public Health Researcher, India
At Pubrica, we offer tailored Health Economics & Outcome Research packages designed to meet the needs of researchers, pharmaceutical companies, healthcare providers, and policymakers. Our evidence-based solutions help demonstrate product value, inform decision-making, and improve patient outcomes.

Basic
- Ideal For: Early-stage researchers, academic submissions, and pilot projects.
- Includeds:
- Literature review & evidence synthesis
- Basic cost analysis (cost-minimization, cost-description)
- Summary tables & graphs
- Draft manuscript/report preparation
- Optional Add-ons:
- Journal selection support
- Editing & proofreading
- Turnaround Time: 2–3 weeks

Standard
- Ideal For: Research teams, healthcare providers, and industry professionals needing publication-ready outcomes.
- Includeds:
- Full economic evaluation (CEA, CUA, CBA)
- Real-world data integration
- Patient-reported outcome (PRO) assessments
- Compliance with international HEOR guidelines (ISPOR, NICE, FDA/EMA)
- Detailed results interpretation & visualization
- Optional Add-ons:
- Statistical modeling support
- Budget impact analysis
- Peer review response assistance
- Journal submission management
- Optional Add-ons: 8-12 weeks

Premium
- Ideal For: Pharma, biotech, and med-tech companies requiring strategic HEOR support for reimbursement and market access.
- Includeds:
- Advanced modeling (Markov, decision-tree, survival analysis)
- Budget impact analysis & cost-effectiveness modeling
- Real-world evidence (RWE) generation
- Value dossiers & HTA submission support
- Publication-ready deliverables with regulatory alignment
- Optional Add-ons:
- Advisory board presentation materials
- Conference abstracts & posters
- End-to-end publication management
- Optional Add-ons: 14-16 weeks
Frequently Asked Questions – Health Economics & Outcome Research
HEOR provides evidence that demonstrates the value, cost-effectiveness, and real-world impact of a product. This evidence supports regulatory approvals, reimbursement decisions, and market access strategies.
- Pharmaceutical and biotechnology companies
- Medical device manufacturers
- Payers and insurance providers
- Policymakers and regulators
- Academic researchers and healthcare providers
HEOR includes:
- Cost-effectiveness analysis (CEA)
- Budget impact analysis (BIA)
- Cost-utility analysis (CUA)
- Real-world evidence (RWE) studies
- Patient-reported outcomes (PROs)
- Systematic literature reviews and meta-analyses
- Health technology assessment (HTA) submissions
By providing robust economic models and real-world data, HEOR demonstrates how a treatment improves patient outcomes while being cost-effective. This evidence helps companies negotiate pricing, reimbursement, and formulary placement with payers and regulators.
HEOR helps providers understand which treatments deliver the best outcomes for patients at sustainable costs, guiding evidence-based care delivery and resource allocation.
Yes. Many HEOR studies are published in reputed journals such as Value in Health, Pharmacoeconomics, and Health Economics. We also support clients in manuscript writing and submission.
- Multidisciplinary team of health economists, statisticians, and clinical experts
- Global compliance with ISPOR, HTA, and regulatory guidelines
- Advanced modeling and AI/ML-driven analytics
- End-to-end support from study design to publication
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